Available in several brand names 1 mg/m L in 30m L prednisone oral solution/syrup 2.5 mg, 5 mg, 10 mg and 20 mg prednisone tablets 10 mg/m L prednisone injectable suspension 15 mg/5m L in 240m L prednisolone syrup 5 mg and 20mg prednisolone tablets Prednisone and prednisolone are synthetic members of the glucocorticoid class of hormones. They are an intermediate acting, broad anti-inflammatory, medication. Typically stating, this means that the action of one dose lasts from a day to a day and a half. Prednisone and prednisolone have less activity than the longer acting dexamethasone or betamethasone, but exhibit greater activity than hydrocortisone. Though prednisone and prednisolone are used in the same manner and equally as effective, they should not be confused with each other. Prednisone is activated by the liver into prednisolone. For this reason, and because it is more easily absorbed, prednisolone is the drug of choice when hepatic disease or insufficiency is present. Prednisolone is a precursor and an active form of prednisone. Moreover, the former has higher bioavailability than the latter. The following Health Hearty article gives a prednisone vs. Prednisone is the most commonly prescribed synthetic corticosteroid for arthritis, and 5 mg of prednisone is equivalent to the body's daily output of cortisol―a hormone that allows the body to cope with stressful situations, such as trauma, surgery, infection, or emotional problems. Both prednisone and prednisolone are classified as corticosteroids―drugs that help reduce inflammatory response of the immune system. These medications act as excellent anti-inflammatory agents that suppress the immune system, which works to reduce the inflammatory response associated with a wide range of auto-immune disorders such as asthma, ulcerative colitis, rheumatoid arthritis, and inflammatory skin problems. Veterinarians also prescribe these drugs to treat inflammatory conditions in dogs and cats. Since both drugs are used for the same purpose, i.e., to treat anti-inflammatory conditions, even the side effects are more or less the same, which may lead us to believe that there is no difference between prednisone and prednisolone.
Prednisone and prednisolone are corticosteroids indicated to treat or manage many conditions, including endocrine disorders, rheumatic disorders, collagen. Dec 15, 2012. Prednisone and prednisolone are used in a wide variety of diseases. The two compounds are metabolically interconvertible; prednisolone is.