If you have been suffering from a Candida or yeast infection, your doctor may prescribe you a prescription antifungal medication named Diflucan, or to use the generic name, fluconazole. This antifungal is well-researched and has been around for a long time, but it does come with side effects. There are also concerns that fungal pathogens like Candida albicans may be developing resistance to it. Be aware that, although Diflucan can be an effective choice, there are natural antifungals that have been shown to be as effective (and sometimes even more effective). Choosing a natural antifungal may offer the same benefits as a prescription antifungal, but with fewer side effects and less stress on your liver and detoxification pathways. (1, 2)Antifungal medications and natural antifungals will work best when combined with lifestyle changes. You should address whatever caused your Candida (diet, antibiotics, antacids, etc) for the best chance of eliminating your Candida infection ad preventing it from coming back. Consumer Medicine Information Please read this leaflet before you take Diflucan® One. Thrush is the common name given to a vaginal yeast infection. Most women experience vaginal thrush at some point during their lives. If this is the first time you have had these symptoms, talk to your doctor before using any treatment. Vaginal yeast infections are caused by Candida, a type of yeast. Many women have this yeast living harmlessly within their bodies. However, some factors can cause an upset in the natural balance inside the vagina and an overgrowth of yeast can occur. These factors may include use of antibiotics, hormonal changes (during pregnancy, menstruation, menopause), diabetes, the contraceptive pill, wearing tight clothing, or using perfumed soaps, bath additives and vaginal deodorants.
This content has not been reviewed within the past year and may not represent Web MD's most up-to-date information. To find the most current information, please enter your topic of interest into our search box. 25, 2005 -- Most women experience vaginal yeast infections at some point in their lives, but an unfortunate few get them again and again. Preventing repeated infections has been an elusive goal for the roughly 5% of women who have recurrent vaginal yeast infections, but new research should change that. The antifungal drug Diflucan, taken just once a week, was found to reduce the frequency of infections by more than 90% in a six-month study involving nearly 400 women with a history of recurrent candida vaginal infections. Sobel, MD, tells Web MD that the drug represents the first safe and highly effective preventive therapy for women with recurrent vaginal yeast infections, defined as those occurring four or more times a year. "The responses we saw in this study were remarkable," he says. "For many patients, this treatment gave them back a normal life." The women treated with Diflucan initially took three 150-milligram oral doses of the drug at 72-hour intervals, followed by a weekly 150-milligram dose taken for six months. By the end of the six-month treatment period just 8% of the women on Diflucan had experienced recurrences, compared with 64% of women in the study given a placebo pill. Fluconazole is a first-generation triazole antifungal medication. It differs from earlier azole antifungals (such as ketoconazole) in that its structure contains a triazole ring instead of an imidazole ring. While the imidazole antifungals are mainly used topically, fluconazole and certain other triazole antifungals are preferred when systemic treatment is required because of their improved safety and predictable absorption when administered orally. Fluconazole's spectrum of activity includes most Candida species (but not Candida krusei or Candida glabrata), Cryptococcus neoformans, some dimorphic fungi, and dermatophytes, among others. Common uses include: Fungal resistance to drugs in the azole class tends to occur gradually over the course of prolonged drug therapy, resulting in clinical failure in immunocompromised patients (e.g., patients with advanced HIV receiving treatment for thrush or esophageal Candida infection). albicans, resistance occurs by way of mutations in the ERG11 gene, which codes for 14α-demethylase. These mutations prevent the azole drug from binding, while still allowing binding of the enzyme's natural substrate, lanosterol. glabrata is increasing the rate of efflux of the azole drug from the cell, by both ATP-binding cassette and major facilitator superfamily transporters. Development of resistance to one azole in this way will confer resistance to all drugs in the class. Other gene mutations are also known to contribute to development of resistance.
How to take Diflucan? Dosages Side effects and precautions. How to buy Diflucan online? Diflucan antifungal tablets are available to order at OnlineClinic in a 150mg dose. According to our partner doctors this is the recommended dosage of Diflucan. You should make sure of taking diflucan or fluconazole for completely prescribed time length. In this way, you will find improvement in your symptomsDiflucan or fluconazole may pass within the breast milk and thereby, may cause harm to any nursing baby. Hence, if you are providing breast milk to a.