Propranolol belongs to a group of medicines called beta blockers. It's used to treat heart problems, help with anxiety and prevent migraines. If you have a heart problem, you can take propranolol to: Propranolol can help reduce your symptoms if you have too much thyroid hormone in your body (thyrotoxicosis). You'll usually take it together with medicines to treat an overactive thyroid. It comes as tablets, capsules, or as a liquid to swallow Propranolol can be taken by adults and children. But it is not officially approved for treating high blood pressure in children under 12 years old. To make sure it is safe for you, tell your doctor before starting propranolol if you have: If you are taking it once a day, your doctor may advise you to take your first dose before bedtime, because it can make you feel dizzy. After the first dose, if you don't feel dizzy, take propranolol in the morning. Doses are usually lower for the elderly or people with a kidney or liver problem. The NICE British National Formulary (BNF) and British National Formulary for Children (BNFc) sites are only available to users in the UK, Crown Dependencies and British Overseas Territories. If you believe you are seeing this page in error please contact us.
Key clinical point: A single 40-mg dose of oral propranolol, judiciously timed, is a highly promising novel treatment for anxiety disorders. Major finding: The beta-blocker must be given within an hour before to an hour after therapist-facilitated reactivation of the fear memory. Study details: This study included 30 healthy volunteers who underwent a cued Pavlovian fear-conditioning program. Soeter’s study of the time- and sleep-dependent nature of propranolol-induced amnesia was supported by the Netherlands Organization for Scientific Research, where she is employed.– A single 40-mg dose of oral propranolol, judiciously timed, constitutes an outside-the-box yet highly promising treatment for anxiety disorders, and perhaps for posttraumatic stress disorder as well, Marieke Soeter, Ph D, said at the annual congress of the European College of Neuropsychopharmacology. The concept here is that the beta-blocker, when given with a brief therapist-led reactivation of a fear memory, blocks beta-adrenergic receptors in the brain so as to interfere with the specific proteins required for reconsolidation of that memory, thereby disrupting the reconsolidation process and neutralizing subsequent expression of that memory in its toxic form. In effect, timely administration of one dose of propranolol, a drug that readily crosses the blood/brain barrier, achieves pharmacologically induced amnesia regarding the learned fear, explained , a clinical psychologist at TNO, the Netherlands Organization for Scientific Research, an independent nonprofit translational research organization.“It looks like permanent fear erasure. You can never say that something is erased, but we have not been able to get it back,” she said. “Propranolol achieves selective erasure: It targets the emotional component, but knowledge is intact. Anxiety impacts millions of people across the world every day. It comes in different forms and impacts each person to a different degree. For some, anxiety can be overwhelming and prevent them from doing things they love to do. Fortunately, there are a variety of medications available to help those who suffer from anxiety. Depending on the diagnosis and symptoms each person experiences, medications may benefit them to different degrees. Working closely with your mental health provider and primary care provider, you can find a medication regimen that will work best for you to manage your anxiety symptoms. THIS ARTICLE IS FOR INFORMATIONAL PURPOSES ONLY AND SHOULD NOT BE TAKEN AS MEDICAL ADVICE.
Mar 14, 2018. Learn about propranolol, a beta-blocker. This article looks at how the drug affects the body and the conditions that it can be used to help treat. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for PROPRANOLOL HYDROCHLORIDE. Anxiety with symptoms such as palpitation, sweating and tremor. By mouth. For Adult.